Vanbu040: ←Created page with ''''C20orf202''' (Chromosome 20 Open Reading Frame 202) is a protein that in humans is encoded by the ''C20orf202'' gene. In humans, this gene en...'
'''C20orf202''' (Chromosome 20 Open Reading Frame 202) is a [[protein]] that in humans is encoded by the ''C20orf202'' [[gene]].
In [[humans]], this [[gene]] encodes for a [[nuclear protein]] that is primarily expressed in the [[lung]] and [[placenta]].<ref></ref>
== Gene ==
C20orf202 is located on the plus strand of chromosome 20 at 20p13.<ref></ref> The gene is 4,826 [[base pairs]] long and contains 2 [[exons]]. <ref></ref>
== Transcript ==
There is only one variant of C20orf202. The [[mRNA]] sequence is 1,609 base pairs long.<ref>Liquid error: wrong number of arguments (given 1, expected 2)</ref>
== Protein ==
The protein encoded by C20orf202 is 122 [[amino acids]] in length with a predicted molecular mass of 13591 Da and a predicted isoelectric point of 9.13 pl/MW.<ref></ref><ref> CT202 Protein CT202 Antibody |url=https://ift.tt/2KEpwZj |website=www.genecards.org |accessdate=27 April 2020}}</ref>
== Homology ==
=== Paralogs ===
C20orf202 has three known paralogs- FAM167a, FAM167b, and AARD.<ref> CT202 Protein CT202 Antibody |url=https://ift.tt/2KEpwZj |website=www.genecards.org |accessdate=27 April 2020}}</ref>
=== Orthologs ===
C20orf202 orthologs can be found in major groups such as [[mammals]], [[reptiles]], [[amphibians]], and distantly fish.
This table lists several orthologs for C20orf202 including genus and species, common name, taxonomic group, date of divergence, accession number, sequence length, sequence length, sequence similarity, and evolutionary date of divergence.
{| class="wikitable"
|+
''C20orf202'' Orthologs
!Genus and species
!Common name
!Taxonomic group
!Estimated date of divergence
!Accession number
!Length (amino acids)
!Sequence identity
!Sequence similarity
|-
|Homo sapiens
|Human
|Mammalia (Primata)
|0
|NP_001009612.1
|122
|100%
|100%
|-
|Heterocephalus glaber
|Naked mole-rat
|Mammalia (Rodentia)
|90
|XP_021110529.1
|248
|79%
|84%
|-
|Ochotona princeps
|American Pika
|Mammalia (Lagomorpha)
|90
|XP_012782703.1
|98
|75%
|85%
|-
|Dipodomys ordii
|Ord's kangaroo rat
|Mammalia (Rodentia)
|90
|XP_012866108.1
|151
|74%
|87%
|-
|Peromyscus maniculatus bairdii
|Deer mouse
|Mammalia (Rodentia)
|90
|XP_006985608.1
|192
|68%
|81%
|-
|Fukomys damarensis
|Damaraland mole-rat
|Mammalia (Rodentia)
|90
|XP_010611217.1
|131
|67%
|77%
|-
|Grammomys surdaste
|African woodland thicket rat
|Mammalia (Rodentia)
|90
|XP_028630806.1
|190
|60%
|71%
|-
|Sus scrofa
|Wild Boar
|Mammalia (Artiodactyla)
|96
|XP_013840663.1
|123
|84%
|90%
|-
|Monodon monoceros
|Narwhal
|Mammalia (Artiodactyla)
|96
|XP_029077716.1
|153
|79%
|90%
|-
|Delphinapterus leucas
|Beluga Whale
|Mammalia (Artiodactyla)
|96
|XP_022448507.1
|153
|79%
|90%
|-
|Orcinus orca
|Orca
|Mammalia (Artiodactyla)
|96
|XP_004273009.1
|136
|78%
|90%
|-
|Eptesicus fuscus
|Big Brown Bat
|Mammalia (Chiroptera)
|96
|XP_028000906.1
|179
|79%
|88%
|-
|Vulpes vulpes
|Red Fox
|Mammalia (Carnivora)
|96
|XP_025841919.1
|163
|79%
|88%
|-
|Canis lupus familiaris
|Dog
|Mammalia (Carnivora)
|96
|XP_022265199.1
|125
|77%
|87%
|-
|Zalophus californianus
|California Sea Lion
|Mammalia (Cetacea)
|96
|XP_027478822.1
|149
|70%
|80%
|-
|Panthera tigris altaica
|Siberian Tiger
|Mammalia (Carnivora)
|96
|XP_007073582.1
|127
|68%
|79%
|-
|Sorex araneus
|Common Shrew
|Mammalia (Eulipotyphla)
|96
|XP_004612739.1
|119
|62%
|71%
|-
|Podarcis muralis
|Common Wall Lizard
|Reptilia (Squamata)
|312
|XP_028591365.1
|95
|45%
|58%
|-
|Alligator sinensis
|Chinese Alligator
|Reptilia (Crocodilia)
|312
|XP_006030613.1
|98
|42%
|59%
|-
|Nanorana parkeri
|High Himalaya frog
|Amphibia (Anura)
|351.8
|XP_018411922.1
|114
|44%
|58%
|-
|Cyprinodon variegatus
|Sheepshead minnow
|Actinopterygii (Cyprinodontiformes)
|435
|XP_015232405.1
|146
|54%
|72%
|}
In [[humans]], this [[gene]] encodes for a [[nuclear protein]] that is primarily expressed in the [[lung]] and [[placenta]].<ref></ref>
== Gene ==
C20orf202 is located on the plus strand of chromosome 20 at 20p13.<ref></ref> The gene is 4,826 [[base pairs]] long and contains 2 [[exons]]. <ref></ref>
== Transcript ==
There is only one variant of C20orf202. The [[mRNA]] sequence is 1,609 base pairs long.<ref>Liquid error: wrong number of arguments (given 1, expected 2)</ref>
== Protein ==
The protein encoded by C20orf202 is 122 [[amino acids]] in length with a predicted molecular mass of 13591 Da and a predicted isoelectric point of 9.13 pl/MW.<ref></ref><ref> CT202 Protein CT202 Antibody |url=https://ift.tt/2KEpwZj |website=www.genecards.org |accessdate=27 April 2020}}</ref>
== Homology ==
=== Paralogs ===
C20orf202 has three known paralogs- FAM167a, FAM167b, and AARD.<ref> CT202 Protein CT202 Antibody |url=https://ift.tt/2KEpwZj |website=www.genecards.org |accessdate=27 April 2020}}</ref>
=== Orthologs ===
C20orf202 orthologs can be found in major groups such as [[mammals]], [[reptiles]], [[amphibians]], and distantly fish.
This table lists several orthologs for C20orf202 including genus and species, common name, taxonomic group, date of divergence, accession number, sequence length, sequence length, sequence similarity, and evolutionary date of divergence.
{| class="wikitable"
|+
''C20orf202'' Orthologs
!Genus and species
!Common name
!Taxonomic group
!Estimated date of divergence
!Accession number
!Length (amino acids)
!Sequence identity
!Sequence similarity
|-
|Homo sapiens
|Human
|Mammalia (Primata)
|0
|NP_001009612.1
|122
|100%
|100%
|-
|Heterocephalus glaber
|Naked mole-rat
|Mammalia (Rodentia)
|90
|XP_021110529.1
|248
|79%
|84%
|-
|Ochotona princeps
|American Pika
|Mammalia (Lagomorpha)
|90
|XP_012782703.1
|98
|75%
|85%
|-
|Dipodomys ordii
|Ord's kangaroo rat
|Mammalia (Rodentia)
|90
|XP_012866108.1
|151
|74%
|87%
|-
|Peromyscus maniculatus bairdii
|Deer mouse
|Mammalia (Rodentia)
|90
|XP_006985608.1
|192
|68%
|81%
|-
|Fukomys damarensis
|Damaraland mole-rat
|Mammalia (Rodentia)
|90
|XP_010611217.1
|131
|67%
|77%
|-
|Grammomys surdaste
|African woodland thicket rat
|Mammalia (Rodentia)
|90
|XP_028630806.1
|190
|60%
|71%
|-
|Sus scrofa
|Wild Boar
|Mammalia (Artiodactyla)
|96
|XP_013840663.1
|123
|84%
|90%
|-
|Monodon monoceros
|Narwhal
|Mammalia (Artiodactyla)
|96
|XP_029077716.1
|153
|79%
|90%
|-
|Delphinapterus leucas
|Beluga Whale
|Mammalia (Artiodactyla)
|96
|XP_022448507.1
|153
|79%
|90%
|-
|Orcinus orca
|Orca
|Mammalia (Artiodactyla)
|96
|XP_004273009.1
|136
|78%
|90%
|-
|Eptesicus fuscus
|Big Brown Bat
|Mammalia (Chiroptera)
|96
|XP_028000906.1
|179
|79%
|88%
|-
|Vulpes vulpes
|Red Fox
|Mammalia (Carnivora)
|96
|XP_025841919.1
|163
|79%
|88%
|-
|Canis lupus familiaris
|Dog
|Mammalia (Carnivora)
|96
|XP_022265199.1
|125
|77%
|87%
|-
|Zalophus californianus
|California Sea Lion
|Mammalia (Cetacea)
|96
|XP_027478822.1
|149
|70%
|80%
|-
|Panthera tigris altaica
|Siberian Tiger
|Mammalia (Carnivora)
|96
|XP_007073582.1
|127
|68%
|79%
|-
|Sorex araneus
|Common Shrew
|Mammalia (Eulipotyphla)
|96
|XP_004612739.1
|119
|62%
|71%
|-
|Podarcis muralis
|Common Wall Lizard
|Reptilia (Squamata)
|312
|XP_028591365.1
|95
|45%
|58%
|-
|Alligator sinensis
|Chinese Alligator
|Reptilia (Crocodilia)
|312
|XP_006030613.1
|98
|42%
|59%
|-
|Nanorana parkeri
|High Himalaya frog
|Amphibia (Anura)
|351.8
|XP_018411922.1
|114
|44%
|58%
|-
|Cyprinodon variegatus
|Sheepshead minnow
|Actinopterygii (Cyprinodontiformes)
|435
|XP_015232405.1
|146
|54%
|72%
|}
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