List of Biosafety level 4 organisms

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[[Biosafety level 4]] laboratories are used for diagnostic work and research on easily transmitted pathogens which can cause fatal disease. What follows is a list of organisms that require handling with the most severe protocol. Organisms include those harmful to human health, to animal health, or to plant health.<ref name="satl"></ref> The [[Plant Protection and Quarantine Programs]] (PPQ) of the [[Animal and Plant Health Inspection Service]] (APHIS) are listed in 7 CFR Part 331. The [[Department of Health and Human Services]] (HHS) lists are located at 42 CFR Part 73.3<ref></ref> and 42 CFR Part 73.4.<ref></ref> The USDA animal safety list is located at 9 CFR Subchapter B.<ref></ref>

==Select Agents==
===HHS Human threats: SELECT AGENTS AND TOXINS===
* Abrin
* Bacillus cereus Biovar anthracis*
*Botulinum neurotoxins*,5
*Botulinum neurotoxin producing species of Clostridium*
*Conotoxins (Short, paralytic alpha conotoxins containing the following amino acid sequence X1CCX2PACGX3X4X5X6CX7)1,5
*Coxiella burnetii
*Crimean-Congo haemorrhagic fever virus
*Diacetoxyscirpenol
*Eastern Equine Encephalitis virus
*Ebola virus
*Francisella tularensis
*Lassa fever virus
*Lujo virus
*Marburg virus
*Monkeypox virus
*Reconstructed 1918 Influenza virus
*Ricin
*Rickettsia prowazekii
*SARS-associated coronavirus (SARS-CoV)
*Saxitoxin
*Chapare
*Guanarito
*Junin
*Machupo
*Sabia
*Staphylococcal enterotoxins (subtypes A,B,C,D,E)
*T-2 toxin
*Tetrodotoxin
*Far Eastern subtype [[flavivirus]]
*Siberian subtype flavivirus
*Kyasanur Forest disease virus
*Omsk hemorrhagic fever virus
*Variola major virus (Smallpox virus)
*Variola minor virus (Alastrim)
*Yersinia pestis

===HHS Human or animal threats: SELECT AGENTS AND TOXINS===
*Bacillus anthracis
*Bacillus anthracis Pasteur strain
*Brucella abortus
*Brucella melitensis
*Brucella suis
*Burkholderia mallei
*Burkholderia pseudomallei
*Hendra virus
*Nipah virus
*Rift Valley fever virus
*Venezuelan equine encephalitis virus

===USDA SELECT AGENTS AND TOXINS===
*African horse sickness virus
*African swine fever virus
*Avian influenza virus
*Classical swine fever virus
*Foot-and-mouth disease virus
*Goat pox virus
*Lumpy skin disease virus
*Mycoplasma capricolum
*Mycoplasma mycoides
*Newcastle disease virus
*Peste des petits ruminants virus
*Rinderpest virus
*Sheep pox virus
*Swine vesicular disease virus

===PPQ SELECT AGENTS AND TOXINS===
*Coniothyrium glycines (formerly Phoma glycinicola and Pyrenochaeta glycines)
*Peronosclerospora philippinensis
*(Peronosclerospora sacchari)
*Ralstonia solanacearum
*Rathayibacter toxicus
*Sclerophthora rayssiae
*Synchytrium endobioticum
*Xanthomonas oryzae

==References==


[[Category:Safety]]
[[Category:Biological hazards]]
[[Category:Biosafety level 4 laboratories]]

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